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Utilizing Bioinformatics to Bring Clarity from Complexity

zetobit empowers scientific discovery by providing expert bioinformatics services, transforming complex biological data into actionable insights for researchers in genomics, transcriptomics, proteomics, and metabolomics. We partner with clients to deliver high-quality, reliable results, accelerating research and improving human health.

Our Services

Our bioinformatics services cover the entire research pipeline. We provide expert guidance in experimental design, ensuring robust and impactful studies. Our state-of-the-art sequencing capabilities deliver high-quality data with industry-leading turnaround times. Furthermore, our team of experienced bioinformaticians offers in-depth data analysis, interpretation, and visualization, empowering you to gain deeper insights from your research. We can plug in anywhere within the process.

We specialize in expert data curation for public dataset analysis, ensuring your research is built on a solid foundation of accurate, consistent, and well-organized information. Our services streamline the often time-consuming process of data cleaning, annotation, and integration, allowing you to focus on extracting meaningful insights and accelerating your research outcomes.

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Data Curation

CCLE UK BioBank TCGA dbGaP
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Public Dataset Analysis

We streamline your data analysis process through the development and implementation of custom bioinformatics pipelines and workflows. Tailored to your specific data needs and research objectives, these solutions automate complex analyses, ensuring consistency, reproducibility, and efficiency, ultimately accelerating your time to discovery.

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Experimental Design

Designing a successful experiment is the foundation of impactful research. Our bioinformatics services include expert consultation to help you develop robust experimental designs tailored to your research questions. We'll work with you to optimize every stage, from sample preparation to data acquisition, ensuring your data is of the highest quality and maximizes your chances of achieving your research goals.

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Sequencing Services

Experience the difference of high-quality sequencing combined with exceptional speed. Our cutting-edge technology and optimized workflows deliver accurate and reliable data with industry-leading turnaround times, empowering you to achieve your research goals faster.

Sequencing
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Proprietary Dataset Analysis & Visualization

Our bioinformatics services go beyond basic analysis. We offer expert analytical support from experienced subject-matter experts who can help you interpret your results in the context of existing research. We leverage publicly available datasets for comparative analysis, providing a deeper understanding of your findings and unlocking new avenues for discovery.

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Our Team

Kanna Nandakumar

Kanna Nandakumar, PhD

Founder and CEO

Dr. Nandakumar is a leading bioinformatics expert with over 14 years of experience driving innovation in genomics and personalized medicine. With a proven track record of developing and implementing CAP/CLIA compliant clinical bioinformatics pipelines, including NGS-based cancer panels and constitutional disorder panels, he empowers healthcare providers with actionable insights. His expertise spans the entire spectrum of genomic data analysis, from WGS and medical exome to targeted panels and RNA-seq. As the founder of zetobit, Dr. Nandakumar is dedicated to providing cutting-edge bioinformatics solutions tailored to meet the unique needs of each client.

LinkedIn Google Scholar
Justin Duplantis

Justin Duplantis, MBA

Chief Business Officer

Justin is a results-driven Business Development Manager with a proven track record of driving exponential growth in the life sciences industry. Combining a strong scientific background (BS Chemistry, MBA Data Analytics) with over five years of industry experience and two decades of sales expertise, Justin excels at developing and executing successful sales and marketing strategies. His expertise includes building high-performing teams, cultivating strategic partnerships with key stakeholders (including industry leaders, academic institutions, and sequencing providers), and securing significant revenue growth. At zetobit, Justin is focused on connecting clients with our cutting-edge bioinformatics solutions to accelerate their research and achieve their goals.

LinkedIn
Bioinformatics Team

Bioinformatics Team

Global Experts

Our bioinformatics team is a globally distributed group of highly skilled bioinformaticians passionate about accelerating scientific breakthroughs. We combine diverse expertise with a robust scientific partner ecosystem, including leading researchers, institutions, and technology providers, to deliver comprehensive and effective solutions. Driven by a shared commitment to empowering researchers, we work closely with clients, tailoring our services to meet their specific needs and ensuring research goals are achieved efficiently and effectively, from experimental design and data analysis to interpretation and visualization.

Publications

GWAS

GWAS
Nature Genetics Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature genetics 44 (5), 491.
GWAS
Acta Neuropathologica ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta neuropathologica 127 (6), 825-843.
GWAS
Human Molecular Genetics Large common deletions associate with mortality at old age. Human molecular genetics 20 (21), 4290-4296.
GWAS
Journal of Medical Genetics A genome-wide copy number association study of osteoporotic fractures points to the 6p25. 1 locus. Journal of medical genetics, jmedgenet-2013-102064.
GWAS
Human Molecular Genetics Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging. Human molecular genetics 25 (23), 5234-5243.
GWAS
BMC Proceedings On family-based genome-wide association studies with large pedigrees: observations and recommendations. BMC proceedings 8 (1), S26.
GWAS
Springer Mihajlovic, A., Machine Learning-Based Imputation of Missing SNP Genotypes in SNP Genotype Arrays, ISBN 9781461487852, 2013, Computational Medicine in Data Mining and Modeling, Springer New York
GWAS
AACR Prevalence of pathogenic mutations in cancer predisposition genes among pancreatic cancer patients. Cancer Epidemiology and Prevention Biomarkers.

R&D NGS

R&D NGS
Cancer Research The association of glioma germline risk SNPs with mutation-based molecular subgroups. Cancer Research 74 (19 Supplement), 4714-4714.
R&D NGS
bioRxiv Clarke, D, et. al., Playbook Workflow Builder: Interactive Construction of Bioinformatics Workflows from a Network of Microservices, 2024, Cold Spring Harbor Laboratory.
R&D NGS
IEEE Constellation: A secure self-optimizing framework for genomic processing. e-Health Networking, Applications and Services (Healthcom), 2016 IEEE 18th ...

Clinical NGS

Clinical NGS
Cancer Research Lau, J.W., Lehnert E., et. al., The Cancer Genomics Cloud: Collaborative, Reproducible, and Democratized—A New Paradigm in Large-Scale Computational Research, ISSN 1538-7445, DOI 10.1158/0008-5472.can-17-0387, 2017, Cancer Research, American Association for Cancer Research (AACR)
Clinical NGS
IPT Mihajlovic A., AI and its Involvement in the Future of Neoantigen Discovery, 2020, Innovations in Pharmaceutical Technology
Clinical NGS
Bioinformatics Bioinformatics Strategies for Identifying Regions of Epigenetic Deregulation Associated with Aberrant Transcript Splicing and RNA-editing. Bioinformatics, 163-170.

Bulk RNA-seq

Bulk RNA-seq
Nature Scientific Reports Leong P, Mihajlović A, Xi L, et. Al., Reconstructing and counting genomic fragments through tagmentation-based haploid phasing, volume 11, ISSN=2045-2322, September 2021, Nature Scientific Reports, Springer Science and Business Media LLC

scRNA-seq

scRNA-seq
Bio-Protocol Long P, Mihajlovic A., Xi L, Preparing Single-cell DNA Library Using Nextera for Detection of CNV, ISSN 2331-8325, DOI 10.21769/bioprotoc.3175, 2019, BIO-PROTOCOL

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Zetobit, LLC

Location

710 E Main St

Lexington, KY 40502

Contact

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